Gelsemium sempervirens and Panax ginseng are antibacterial plants native to China. They are well-known traditional herbal medicine that play a protective role against microbial attack. The aim of this study is to use DNA-Barcoding in determining the change in the microbiome of the soil at Union Square Park before and after treatment with Gelsemium sempervirens and Panax ginseng solution. This would help us determine if the plants can be used to specific bacteria. It is hypothesized that Gelsemium sempervirens and Panax ginseng will create a significant decrease in the amount of bacteria found in the soil.